Donald Trump on Monday urged Iran and Israel to stop firing "immediately" after direct attacks resumed between the two countries for the first time since the truce agreed two months ago.

After 100 days of war and the entry into force on April 8 of a fragile ceasefire, explosions and alerts have once again been heard in Tehran and Tel Aviv, although no injuries have been reported so far.

Since Sunday evening, Iran has fired around 30 missiles at Israel, according to an Israeli military official, in response to an Israeli strike against the southern suburbs of Beirut, a stronghold of the pro-Iranian Hezbollah, in which two people died and 20 were injured.

These attacks are a "warning" to Tehran, which is threatening a "broader response," while the Islamic Republic considers the two fronts of the conflict to be inseparable.

But Donald Trump, who has made no secret of his disagreements with Israeli Prime Minister Benjamin Netanyahu in recent days, has put his foot down.

"Israel and Iran must immediately stop 'shooting'," urged the US president on his Truth Social network, as he seeks a way out of a conflict that is very unpopular in the United States, with the midterm elections approaching.

- "To relive all of that" -

In Tel Aviv, Hillary Shaw, 68, took refuge in a store shelter, not having one at home, and "hopes that Trump will intervene with Netanyahu so that it doesn't last long".

"It's not much fun waking up so early in the morning and reliving all of this, without knowing how long it will last or what's going on," adds Jonathan Ariel. "Last time, we thought it would be short and it lasted a month," sighs the thirty-something.

Daily life is once again disrupted in Israel: schools are closed, and transportation is disrupted. Near Jericho, in the occupied West Bank, an AFP photographer saw a missile embedded in the ground on a desert hillside while two Israelis inspected it.

In Tehran, a powerful explosion was heard this morning by an AFP journalist, shaking the Foreign Ministry building where he was attending a press conference. According to the Iranian news agency Mehr, it was a drone "belonging to the American-Zionist enemy" that was shot down.

The airspace in western Iran has been closed and flights from both airports in the capital have been suspended.

Traffic was less dense than usual in the capital, with some residents appearing to have stayed home while others took precautions by queuing to fill up their petrol tanks.

Iranians say they are exhausted by this conflict, which began on February 28 with Israeli-American strikes. "The economy is paralyzed, society is suffering from post-traumatic stress, morale is at rock bottom. Nobody knows what tomorrow holds," laments Farhad, a 35-year-old chef.

- Talks "affected" -

A few hours earlier, Iranian state television had reported explosions in Tehran, Tabriz (northwest), and Isfahan (central Iran). A petrochemical plant in Mahshahr (southwest) was damaged and its staff evacuated, according to Iranian media.

In response, Iran said it had launched strikes against an Israeli petrochemical complex. The judiciary warned that publishing any images of sites affected by the strikes would be subject to prosecution.

Israel, for its part, indicated that it had struck and destroyed defense systems in Iran. "No self-respecting country would tolerate such an attack," commented Israeli Ambassador to the United States Yechiel Leiter on X.

While skirmishes have taken place in recent days around the Strait of Hormuz between the United States and Iran, this is the first time there have been reciprocal attacks on their soil between Iran and Israel since the ceasefire of April 8.

This resumption of hostilities will "affect" talks with the United States even if negotiations via the Pakistani mediator continue, Iranian diplomacy asserts, a point confirmed by Donald Trump, who lamented that the process was being hampered by "ignorance or stupidity."

The Middle East "does not need an escalation," lamented the European Union's foreign policy chief Kaja Kallas, while Beijing said it was "deeply concerned."

- Oil prices are rising -

Fueling fears of a further escalation of the conflict, the Houthi rebels in Yemen, allied with Iran, claimed responsibility for an attack against Israel from Yemen and decreed a ban on Israeli navigation in the Red Sea, another strategic maritime route.

In this tense context, oil prices, which have already soared in recent weeks due to the blockade of the Strait of Hormuz, were climbing: around 09:00 GMT, the barrel of Brent, the European reference, rose by 4.90% to $97.65.

And global stock markets were trading in the red in the face of this "fragile and unpredictable situation", according to a financial analyst.

These attacks further diminish the prospect of a possible agreement to end this war.

Especially since, besides Lebanon, there are still many sticking points: control of the Strait of Hormuz (essential for hydrocarbon trade), the Iranian nuclear program and its stockpile of highly enriched uranium, or the fate of Iranian assets frozen abroad under the effect of sanctions.